Article
FSHB -211G>T stratification for follicle-stimulating hormone treatment of male infertility patients: making the case for a pharmacogenetic approach in genetic functional secondary hypogonadism.
Andrology - 1 Nov 2015
Busch A S, Kliesch S, Tüttelmann F, Gromoll J
Abstract excerpt
Male infertility contributes to a substantial share to couple infertility. Despite scientific efforts, most cases of male infertility remain 'idiopathic' and male-specific therapeutic options are sparse. Given the crucial role of the follicle-stimulating hormone (FSH) for spermatogenesis, FSH is used empirically to improve semen parameters. Furthermore, a recently updated Cochrane review points to a beneficial...
Topics
- Female
- Fertility
- Fertility Agents
- Follicle Stimulating Hormone
- Follicle Stimulating Hormone, beta Subunit
- Genotype
- Humans
- Infertility, Male
- Male
- Pharmacogenetics
- Phenotype
- Polymorphism, Single Nucleotide
- Pregnancy
- Reproductive Techniques, Assisted