FSHB -211G>T stratification for follicle-stimulating hormone treatment of male infertility patients: making the case for a pharmacogenetic approach in genetic functional secondary hypogonadism.

doi:10.1111/andr.12094

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Article

FSHB -211G>T stratification for follicle-stimulating hormone treatment of male infertility patients: making the case for a pharmacogenetic approach in genetic functional secondary hypogonadism.

Andrology - 1 Nov 2015

Busch A S, Kliesch S, Tüttelmann F, Gromoll J

Abstract excerpt

Male infertility contributes to a substantial share to couple infertility. Despite scientific efforts, most cases of male infertility remain 'idiopathic' and male-specific therapeutic options are sparse. Given the crucial role of the follicle-stimulating hormone (FSH) for spermatogenesis, FSH is used empirically to improve semen parameters. Furthermore, a recently updated Cochrane review points to a beneficial...

Read the complete abstract on PubMed

Topics

Female
Fertility
Fertility Agents
Follicle Stimulating Hormone
Follicle Stimulating Hormone, beta Subunit
Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Humans

Infertility, Male

Male

Pharmacogenetics

Phenotype

Polymorphism, Single Nucleotide

Pregnancy

Reproductive Techniques, Assisted

Treatment Outcome

Source

Open in PubMed

Identifiers

PMID: 26445243
DOI: 10.1111/andr.12094

Genes

FSHB
FSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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