[FSH and FSHR gene polymorphisms and male infertility: An update].

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Article

[FSH and FSHR gene polymorphisms and male infertility: An update].

Zhonghua nan ke xue = National journal of andrology - 1 Nov 2015

Wu Qiu-yue, Shui Ying-chun, Xia Xin-yi, Huang Yu-feng

Abstract excerpt

Follicle-stimulating hormone (FSH) is synthesized and secreted by the anterior pituitary, which binds to its receptors expressed on the membrane of Sertoli cells in the testis to bring about spermatogenesis. With the development of DNA sequencing technology, FSH SNPs rs10835638 and FSHR SNPs rs6165, rs6166, and rs1394205 were detected, which might directly affect the expression of FSH and activity of FSHR,...

Topics

Follicle Stimulating Hormone
Humans
Infertility, Male
Male
Polymorphism, Single Nucleotide
Receptors, FSH
Sertoli Cells
Spermatogenesis
Testis

Source

Open in PubMed

Identifiers

PMID: 26738333

Genes

FSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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