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Sirtuins are crucial regulators of T cell metabolism and functions

16 Mar 2022

Abstract excerpt

Abstract It is well known that metabolism underlies T cell differentiation and functions. The pathways regulating T cell metabolism and function are interconnected, and changes in T cell metabolic activity directly impact the effector functions and fate of T cells. Thus, understanding how metabolic pathways influence immune responses and ultimately affect disease progression is paramount. Epigenetic and...

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PMID: 35296782
DOI: 10.1038/s12276-022-00739-7

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