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Article

Multiple Roles of SIRT2 in Regulating Physiological and Pathological Signal Transduction

29 Aug 2022

Abstract excerpt

Sirtuin 2 (SIRT2), as a member of the sirtuin family, has representative features of evolutionarily highly conserved nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase activity. In addition, SIRT2, as the only sirtuin protein colocalized with tubulin in the cytoplasm, has its own functions and characteristics. In recent years, studies have increasingly shown that SIRT2 can participate in the...

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PMID: 36101744
DOI: 10.1155/2022/9282484

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