Article
Integrative Genomic Profiling Uncovers Therapeutic Targets of Acral Melanoma in Asian Populations.
Clinical cancer research : an official journal of the American Association for Cancer Research - 13 Jun 2022
Shi Qiong, Liu Lin, Chen Jianru, Zhang Weigang, Guo Weinan, Wang Xiao, Wang Huina, Guo Sen, Yue Qiao, Ma Jingjing, Liu Yu, Zhu Guannan, Zhao Tao, Zhao Jianhong, Liu Ying, Gao Tianwen, Li Chunying
Abstract excerpt
PURPOSE: Acral melanoma is the major subtype of melanoma seen in Asian patients with melanoma and is featured by its insidious onset and poor prognosis. The genomic study that elucidates driving mutational events is fundamental to the development of gene-targeted therapy. However, research on genomic profiles of acral melanoma in Asian patients is still sparse. EXPERIMENTAL DESIGN: We carried out whole-exome...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.