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Oncogenic signaling pathways and hallmarks of cancer in Korean patients with acral melanoma.

Computers in biology and medicine - 1 Mar 2023

Moon SeongRyeol, Kim Hee Joo, Lee Yeeun, Lee Yu Joo, Jung Sungwon, Lee Jin Sook, Hahn Si Houn, Kim Kyungdoc, Roh Joo Young, Nam Seungyoon

Abstract excerpt

Acral melanoma (AM), a rare subtype of cutaneous melanoma, shows higher incidence in Asians, including Koreans, than in Caucasians. However, the genetic modification associated with AM in Koreans is not well known and has not been comprehensively investigated in terms of oncogenic signaling, and hallmarks of cancer. We performed whole-exome and RNA sequencing for Korean patients with AM and acquired the genetic...

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PMID: 36716688
DOI: 10.1016/j.compbiomed.2023.106602

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