Article
Distinct genomic traits of acral and mucosal melanomas revealed by targeted mutational profiling.
Pigment cell & melanoma research - 1 Jul 2020
Zou Zhengyun, Ou Qiuxiang, Ren Yu, Lv Qing, Qin Lanqun, Zhao Lianjun, Su Shu, Wu Xue, Bao Hua, Wang Ao, Zhu Dongqin, Wang Xiaonan, Shao Yang W, Liu Baorui
Abstract excerpt
The incidence of melanoma is rising globally including China. Comparing to Caucasians, the incidence of non-cutaneous melanomas is significantly higher in Chinese. Herein, we performed genomic profiling of 89 Chinese surgically resected primary melanomas, including acral (n = 54), cutaneous (n = 22), and mucosal (n = 13), by hybrid capture-based next-generation sequencing. We show that mucosal melanomas tended to...
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