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Genomic landscape of cutaneous, acral, mucosal, and uveal melanoma in Japan: analysis of clinical comprehensive genomic profiling data.

International journal of clinical oncology - 1 Dec 2024

Hida Tokimasa, Kato Junji, Idogawa Masashi, Tokino Takashi, Uhara Hisashi

Abstract excerpt

BACKGROUND: Cutaneous melanoma (CM) is the most common type in Caucasians, while acral melanoma (AM) and mucosal melanoma (MM), which are resistant to immunotherapies and BRAF/MEK-targeted therapies, are more common in East Asians. Genomic profiling is essential for treating melanomas, but such data are lacking in Japan. METHODS: Comprehensive genomic profiling data compiled in the Center for Cancer Genomics and...

Topics

Humans
Melanoma
Uveal Neoplasms
Japan
Female
Male
Mutation
Middle Aged
Aged
Skin Neoplasms
Aged, 80 and over
Adult

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genomics

Melanoma, Cutaneous Malignant

Proto-Oncogene Proteins B-raf

Mucous Membrane

Uveal Melanoma

Source

Identifiers

PMID: 39249554
DOI: 10.1007/s10147-024-02615-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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