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Article

Genomic landscape of cutaneous, acral, mucosal, and uveal melanoma in Japan: analysis of clinical comprehensive genomic profiling data.

International journal of clinical oncology - 1 Dec 2024

Hida Tokimasa, Kato Junji, Idogawa Masashi, Tokino Takashi, Uhara Hisashi

Abstract excerpt

BACKGROUND: Cutaneous melanoma (CM) is the most common type in Caucasians, while acral melanoma (AM) and mucosal melanoma (MM), which are resistant to immunotherapies and BRAF/MEK-targeted therapies, are more common in East Asians. Genomic profiling is essential for treating melanomas, but such data are lacking in Japan. METHODS: Comprehensive genomic profiling data compiled in the Center for Cancer Genomics and...

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Source

Identifiers

PMID: 39249554
DOI: 10.1007/s10147-024-02615-y

Genes

KIT
BRAF
CDKN2A
NF1
NRAS
CDKN2B
MYC
BAP1
CAT
CCND1
CDK4
GNA11
GNAQ
MDM2
SF3B1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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