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Qualitative and Quantitative Analysis of DNA Cytidine Deaminase Activity.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

DeWeerd Rachel, Green Abby M

Abstract excerpt

The human genome encodes eleven DNA cytidine deaminases in the AID/APOBEC family, which encompass endogenous roles ranging from genetic diversification of the immunoglobulin locus to virus restriction. All AID/APOBEC functions are enabled by their catalyzation of cytidine deamination resulting in mutations and DNA damage. When acting aberrantly, deaminases can cause off-target mutations in the cellular genome...

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PMID: 35290637
DOI: 10.1007/978-1-0716-2063-2_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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