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Article

Dihydronicotinamide Riboside Is a Potent NAD+ Precursor Promoting a Pro-Inflammatory Phenotype in Macrophages.

Frontiers in immunology - 1 Jan 2022

Chini Claudia C S, Peclat Thais R, Gomez Lilian S, Zeidler Julianna D, Warner Gina M, Kashyap Sonu, Mazdeh Delaram Z, Hayat Faisal, Migaud Marie E, Paulus Aneel, Chanan-Khan Asher A, Chini Eduardo N

Abstract excerpt

Nicotinamide adenine dinucleotide (NAD) metabolism plays an important role in the regulation of immune function. However, a complete picture of how NAD, its metabolites, precursors, and metabolizing enzymes work together in regulating immune function and inflammatory diseases is still not fully understood. Surprisingly, few studies have compared the effect of different forms of vitamin B3 on cellular functions....

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Identifiers

PMID: 35281060
DOI: 10.3389/fimmu.2022.840246
PMCID: PMC8913500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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