Article
Prognostic value of HLA class I, HLA-E, HLA-G and Tregs in rectal cancer: a retrospective cohort study.
BMC cancer - 5 Jul 2014
Reimers Marlies S, Engels Charla C, Putter Hein, Morreau Hans, Liefers Gerrit Jan, van de Velde Cornelis J H, Kuppen Peter J K
Abstract excerpt
BACKGROUND: Evasion of immune surveillance and suppression of the immune system are important hallmarks of tumorigenesis. The goal of this study was to establish distinct patterns that reflect a rectal tumors' immune-phenotype and to determine their relation to patient outcome. METHODS: The study population consisted of 495 Stage I-IV non-preoperatively treated rectal cancer patients of which a tissue micro array...
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