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Article

Immuno-epidemiologic mapping of human leukocyte antigen diversity across glioma patient cohorts.

Neuro-oncology - 30 Jul 2025

Xiong Zujian, Walsh Kyle M, Sneiderman Chaim T, Nisnboym Michal, Hadjipanayis Costas G, Agnihotri Sameer, Eagar Todd N, Wang Hong, Pollack Ian F, Forsthuber Thomas G, Li Xuejun, Raphael Itay, Kohanbash Gary

Abstract excerpt

BACKGROUND: Individual-level characteristics underlying population-level variation in glioma risk and outcomes remain incompletely understood. Cancer immunosurveillance, host immunity, and some immunotherapies center on the ability of an individual's immune cells to recognize antigen epitopes presented on major histocompatibility complex molecules. Inter-individual variation in human leukocyte antigen (HLA)...

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Identifiers

PMID: 39949048
DOI: 10.1093/neuonc/noaf040
PMCID: PMC12309715

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