Article
Evidence for an Adult-Like Type 1-Immunity Phenotype of Vδ1, Vδ2 and Vδ3 T Cells in Ghanaian Children With Repeated Exposure to Malaria.
Frontiers in immunology - 1 Jan 2022
León-Lara Ximena, Yang Tao, Fichtner Alina Suzann, Bruni Elena, von Kaisenberg Constantin, Eiz-Vesper Britta, Dodoo Daniel, Adu Bright, Ravens Sarina
Abstract excerpt
Effector capabilities of γδ T cells are evident in Plasmodium infection in young and adult individuals, while children are the most vulnerable groups affected by malaria. Here, we aimed to investigate the age-dependent phenotypic composition of Vδ1+, Vδ2+, and Vδ3+ T cells in children living in endemic malaria areas and how this differs between children that will develop symptomatic and asymptomatic Plasmodium...
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