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Article

Human blood MAIT cell subsets defined using MR1 tetramers

13 Feb 2018

Abstract excerpt

Abstract Mucosal‐associated invariant T (MAIT) cells represent up to 10% of circulating human T cells. They are usually defined using combinations of non‐lineage‐specific (surrogate) markers such as anti‐TRAV1‐2, CD161, IL‐18Rα and CD26. The development of MR1‐Ag tetramers now permits the specific identification of MAIT cells based on T‐cell receptor specificity. Here, we compare these approaches for identifying...

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PMID: 29437263
DOI: 10.1111/imcb.12021

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