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Article

Postnatal Expansion, Maturation, and Functionality of MR1T Cells in Humans.

Frontiers in immunology - 1 Jan 2020

Swarbrick Gwendolyn M, Gela Anele, Cansler Meghan E, Null Megan D, Duncan Rowan B, Nemes Elisa, Shey Muki, Nsereko Mary, Mayanja-Kizza Harriet, Kiguli Sarah, Koh Jeffrey, Hanekom Willem A, Hatherill Mark, Lancioni Christina, Lewinsohn David M, Scriba Thomas J, Lewinsohn Deborah A

Abstract excerpt

MR1-restricted T (MR1T) cells are defined by their recognition of metabolite antigens presented by the monomorphic MHC class 1-related molecule, MR1, the most highly conserved MHC class I related molecule in mammalian species. Mucosal-associated invariant T (MAIT) cells are the predominant subset of MR1T cells expressing an invariant TCR α-chain, TRAV1-2. These cells comprise a T cell subset that recognizes and...

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Identifiers

PMID: 33042140
DOI: 10.3389/fimmu.2020.556695
PMCID: PMC7524872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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