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Article

Homozygous Mutation of gsdf Causes Infertility in Female Nile Tilapia (Oreochromis niloticus).

Frontiers in endocrinology - 1 Jan 2022

Jiang Dong-Neng, Peng You-Xing, Liu Xing-Yong, Mustapha Umar Farouk, Huang Yuan-Qing, Shi Hong-Juan, Li Ming-Hui, Li Guang-Li, Wang De-Shou

Abstract excerpt

Gonadal somatic cell-derived factor (Gsdf) is a member of the TGF-β superfamily, which exists mainly in fishes. Homozygous gsdf mutations in Japanese medaka and zebrafish resulted in infertile females, and the reasons for their infertility remain unknown. This study presents functional studies of Gsdf in ovary development using CRISPR/Cas9 in Nile tilapia (Oreochromis niloticus). The XX wild type (WT) female fish...

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Identifiers

PMID: 35242110
DOI: 10.3389/fendo.2022.813320
PMCID: PMC8886716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Homozygous Mutation of gsdf Causes Infertility in Female Nile Tilapia (Oreochromis niloticus).PMID 35242110Read ↗

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