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Article

Homozygous mutation of foxh1 arrests oogenesis causing infertility in female Nile tilapia†.

Biology of reproduction - 13 Mar 2020

Tao Wenjing, Shi Hongjuan, Yang Jing, Diakite Hamidou, Kocher Thomas D, Wang Deshou

Abstract excerpt

Foxh1, a member of fox gene family, was first characterized as a transcriptional partner in the formation of the Smad protein complex. Recent studies have shown foxh1 is highly expressed in the cytoplasm of oocytes in both tilapia and mouse. However, its function in oogenesis remains unexplored. In the present study, foxh1-/- tilapia was created by CRISPR/Cas9. At 180 dah (days after hatching), the foxh1-/- XX...

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Identifiers

PMID: 31837141
DOI: 10.1093/biolre/ioz225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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