Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus.

PLoS genetics - 1 Nov 2015

Li Minghui, Sun Yunlv, Zhao Jiue, Shi Hongjuan, Zeng Sheng, Ye Kai, Jiang Dongneng, Zhou Linyan, Sun Lina, Tao Wenjing, Nagahama Yoshitaka, Kocher Thomas D, Wang Deshou

Abstract excerpt

Variation in the TGF-β signaling pathway is emerging as an important mechanism by which gonadal sex determination is controlled in teleosts. Here we show that amhy, a Y-specific duplicate of the anti-Müllerian hormone (amh) gene, induces male sex determination in Nile tilapia. amhy is a tandem duplicate located immediately downstream of amhΔ-y on the Y chromosome. The coding sequence of amhy was identical to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Anti-Mullerian Hormone

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Duplication

Share to Genetic Linkage

Share to Mutation, Missense

Share to Sex Determination Processes

Share to Tilapia

Share to Y Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 26588702
DOI: 10.1371/journal.pgen.1005678
PMCID: PMC4654491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus.PMID 26588702Read ↗

Roles of anti-Müllerian hormone and its duplicates in sex determination and germ cell proliferation of Nile tilapiaSemantic proximity Read ↗

Homozygous Mutation of gsdf Causes Infertility in Female Nile Tilapia (Oreochromis niloticus).Semantic proximity Read ↗

Allelic variant in the anti-Müllerian hormone gene leads to autosomal and temperature-dependent sex reversal in a selected Nile tilapia line.Semantic proximity Read ↗

A Y-linked anti-Müllerian hormone duplication takes over a critical role in sex determination.Semantic proximity Read ↗

<i>gsdf</i> is a downstream gene of <i>dmrt1</i> that functions in the male sex determination pathway of the Nile tilapiaSemantic proximity Read ↗

A duplicated amh is the master sex-determining gene for Sebastes rockfish in the Northwest Pacific.Semantic proximity Read ↗

A duplication of the Anti-Müllerian hormone gene is associated with genetic sex determination of different Oreochromis niloticus strains.Semantic proximity Read ↗

Homozygous mutation of foxh1 arrests oogenesis causing infertility in female Nile tilapia†.Semantic proximity Read ↗

Dietary aromatase inhibitor treatment converts XY gsdf homozygous mutants to sub-fertile male in Nile tilapia (Oreochromis niloticus)Semantic proximity Read ↗

The hotei mutation of medaka in the anti-Mullerian hormone receptor causes the dysregulation of germ cell and sexual development.Semantic proximity Read ↗

Female-to-male sex reversal in orange-spotted grouper (Epinephelus coioides) caused by overexpressing of Amh in vivo†Semantic proximity Read ↗

The Tgf-β family member Gdf6Y determines the male sex in <i>Nothobranchius furzeri</i> by suppressing oogenesis-inducing genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.