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Article

<i>gsdf</i> is a downstream gene of <i>dmrt1</i> that functions in the male sex determination pathway of the Nile tilapia

31 Mar 2016

Abstract excerpt

Gonadal soma-derived factor (gsdf) is critical for testicular differentiation in teleosts, yet detailed analysis of Gsdf on testicular differentiation is lacking. In the present study, we knocked out tilapia gsdf using CRISPR/Cas9. F0 gsdf-deficient XY fish with high mutation rate (≥58%) developed as intersex, with ovotestes 90 days after hatching (dah), and become completely sex-reversed with ovaries at 180 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27027772
DOI: 10.1002/mrd.22642

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<i>gsdf</i> is a downstream gene of <i>dmrt1</i> that functions in the male sex determination pathway of the Nile tilapiaPMID 27027772Read ↗

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