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Mutation ofcyp19a1bresults in sterile males due to efferent duct obstruction in Nile tilapia

24 Jul 2019

Abstract excerpt

The involvement of estrogen in male fertility has been well established in mammals. However, less is known about the role of estrogen in fish male reproduction. Our recent study revealed that Cyp19a1a deficiency had no effect on fertility in male fish. In this study, expression of Cyp19a1b, but not Cyp19a1a, was detected by immunohistochemistry in Leydig cells of tilapia testes. cyp19a1b mutation resulted in a...

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PMID: 31339195
DOI: 10.1002/mrd.23237

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