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Article

Mutation of Gonadal soma-derived factor induces medaka XY gonads to undergo ovarian development.

Biochemical and biophysical research communications - 6 Nov 2015

Imai Takuto, Saino Kentaro, Matsuda Masaru

Abstract excerpt

Gonochoristic species have a bipotential gonad that develops into a testis or an ovary. In species whose sex is determined by a genetic factor, the expression of a sex-determining gene is the first cue that directs the development of a bipotential gonad. Subsequent expression of downstream genes induces the gonad to develop into a testis or an ovary. The TGF-ß family member Gonadal soma-derived factor (Gsdf) is...

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PMID: 26408909
DOI: 10.1016/j.bbrc.2015.09.112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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