Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and in silico Analysis of Nonsense SNPs of Human Colorectal Cancer Protein.

Journal of oleo science - 1 Jan 2022

Wang Lu, Tu Huiyang, Zeng Lingzhi, Gao Ruichen, Luo Sumei, Xiong Chao

Abstract excerpt

Colorectal cancer (CRC) is the third most prevalent disease in the world, with an estimated 1.2 million new cases each year. Spontaneous CRCs account for around 70% of all CRCs, are caused by somatic mutations. Minor variations or single-nucleotide polymorphisms (SNPs) in oncogene or tumor-suppressor genes cause familial CRC. MSH2 and MSH6 genes are located on chromosome 2. These genes products are involved in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to DNA-Binding Proteins
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 35236796
DOI: 10.5650/jos.ess21313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and in silico Analysis of Nonsense SNPs of Human Colorectal Cancer Protein.PMID 35236796Read ↗

Investigation on the role of nsSNPs in HNPCC genes--a bioinformatics approach.Semantic proximity Read ↗

Identification of SNPs in hMSH3/MSH6 interaction domain affecting the structure and function of MSH2 protein.Semantic proximity Read ↗

CoDP: predicting the impact of unclassified genetic variants in MSH6 by the combination of different properties of the protein.Semantic proximity Read ↗

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.Semantic proximity Read ↗

Evidence of colorectal cancer risk associated variant Lys25Ser in the proximity of human bone morphogenetic protein 2.Semantic proximity Read ↗

Integrated analysis of unclassified variants in mismatch repair genes.Semantic proximity Read ↗

Computational and Mass Spectrometry-Based Approach Identify Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in JMJD6.Semantic proximity Read ↗

Rare single‐nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndromeSemantic proximity Read ↗

An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET GeneSemantic proximity Read ↗

Prediction of deleterious non-synonymous SNPs of human MDC1 gene: an in silico approach.Semantic proximity Read ↗

Identification of non-synonymous SNPs Impacting Structure and Function of MLH1 and NBN Proteins: A computational approach.Semantic proximity Read ↗

Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.