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Article

Investigation on the role of nsSNPs in HNPCC genes--a bioinformatics approach.

Journal of biomedical science - 24 Apr 2009

Doss C George Priya, Sethumadhavan Rao

Abstract excerpt

BACKGROUND: A central focus of cancer genetics is the study of mutations that are causally implicated in tumorigenesis. The identification of such causal mutations not only provides insight into cancer biology but also presents anticancer therapeutic targets and diagnostic markers. Missense mutat...

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Topics

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis
Share to Computational Biology
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to Genome, Human

Share to Mutation, Missense

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 19389263
DOI: 10.1186/1423-0127-16-42
PMCID: PMC2682794

Genes

MSH6
MSH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19389263-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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