Article
Absence of Artemisinin Resistance-Associated Mutations in the Plasmodium Falciparum Kelch 13 (K13) Propeller Domain Gene Following Widespread Use of Artemisinin-Based Combination Therapy in Iran.
Acta parasitologica - 16 Dec 2025
Mohammadi Sajjad, Forouzesh Flora, Mehrizi Akram Abouie, Shafi Zahra Sadat Mousavi, Pakdel Javad Dadgar, Raeisi Ahmad, Pirahmadi Sakineh
Abstract excerpt
PURPOSE: Continuous surveillance of Plasmodium falciparum Kelch 13 (pfk13) mutations associated with artemisinin resistance is essential for monitoring the emergence of drug-resistant parasites in malaria-endemic regions. Herein, we have assessed the prevalence of point mutations in the pfk13 gene linked to artemisinin resistance in Iranian P. falciparum isolates, 18 years following the nationwide introduction of...
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