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Article

An analysis of genetically regulated gene expression and the role of co-expression networks across 16 psychiatric and substance use phenotypes.

European journal of human genetics : EJHG - 1 May 2022

Gerring Zachary F, Thorp Jackson G, Gamazon Eric R, Derks Eske M

Abstract excerpt

Genome-wide association studies (GWASs) have identified thousands of risk loci for psychiatric and substance use phenotypes, however the biological consequences of these loci remain largely unknown. We performed a transcriptome-wide association study of 10 psychiatric disorders and 6 substance use phenotypes (GWAS sample size range, N = 9725-807,553) using expression quantitative trait loci data from 532...

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Identifiers

PMID: 35217801
DOI: 10.1038/s41431-022-01037-6
PMCID: PMC9090912

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