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Up-front mutation detection in circulating tumor DNA by droplet digital PCR has added diagnostic value in lung cancer

19 Nov 2022

Abstract excerpt

Identification of actionable mutations in advanced stage non-squamous non-small-cell lung cancer (NSCLC) patients is recommended by guidelines as it enables treatment with targeted therapies. In current practice, mutations are identified by next-generation sequencing of tumor DNA (tDNA-NGS), which requires tissue biopsies of sufficient quality. Alternatively, circulating tumor DNA (ctDNA) could be used for...

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PMID: 36413862
DOI: 10.1016/j.tranon.2022.101589

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