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Detection of clinically-relevant <em>EGFR</em> variations in <em>de novo</em> small cell lung carcinoma by droplet digital PCR.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace - 2 Sept 2022

Venkataram Rajesh, Shetty Vijith, Prasad Kishan, Kille Sonam, Srinivas Teerthanath, Chakraborty Anirban

Abstract excerpt

Targeted therapy that utilizes tyrosine kinase inhibitors (TKIs), specific to epidermal growth factor receptors (EGFR) has changed the landscape of treatment of non-small cell lung cancer (NSCLC). The success or failure of this approach depends on presence of certain variations in the tyrosine kinase domain of EGFR gene. Generally, patients diagnosed with Small cell lung cancer (SCLC) are considered ineligible...

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Identifiers

PMID: 36062504
DOI: 10.4081/monaldi.2022.2280

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