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Article

A systems genetics approach delineates the role of Bcl2 in leukemia pathogenesis.

Leukemia research - 1 Mar 2022

Wang Xinfeng, Bajpai Akhilesh Kumar, Gu Qingqing, Centeno Arthur, Starlard-Davenport Athena, Prins Pjotr, Xu Fuyi, Lu Lu

Abstract excerpt

Leukemia is a group of malignancies of the blood forming tissues, and is characterized by the uncontrolled proliferation of blood cells. In the United States, it accounts for approximately 3.5% and 4% of all cancer-related incidences and mortalities, respectively. The current study aimed to explore the role of Bcl2 and associated genes in leukemia pathogenesis using a systems genetics approach. The transcriptome...

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Identifiers

PMID: 35182904
DOI: 10.1016/j.leukres.2022.106804
PMCID: PMC9272521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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