Article
The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias
15 Sept 2011
Abstract excerpt
The disturbance of apoptosis molecular signaling pathways is involved in carcinogenesis. BCL2 family of proteins is the hallmark of apoptosis regulation. In the last decade, new members of BCL2 gene family were discovered and cloned and were found to be differentially expressed in many types of cancer. BCL2 protein family, through its role in regulation of apoptotic pathways, is possibly related to cancer...