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Article

Bcl‐2 proteins in development, health, and disease of the hematopoietic system

16 Feb 2016

Abstract excerpt

Members of the Bcl-2 protein family regulate cell fate decisions following a variety of developmental cues or stress signals, with the outcomes of cell death or survival, thus shaping multiple mammalian tissues. This review describes in detail how anti- and proapoptotic Bcl-2 proteins contribute to the development and functioning of the fetal and adult hematopoietic systems and how they influence the generation...

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Share to Cell death mechanisms and regulation
Share to Erythrocyte Function and Pathophysiology
Share to Hematopoietic Stem Cell Transplantation

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PMID: 26881825
DOI: 10.1111/febs.13683

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