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Study on the Gene Regulatory Effects in Leukemia Based on Multi-omics Mendelian Randomization, Network Pharmacology, and Functional Validation

2025-09-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Leukemia is a type of malignant hematological disease, for which conventional treatments have limited efficacy, and there is an urgent need for novel therapeutic targets.This study investigates the causal effects of gene expression and plasma proteins on four subtypes of leukemia using a multi-omics integration strategy. <bold>Methods:</bold> Based on publicly a...

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Literature Corpus work
42d19d41-47f2-5117-bfa2-cbde061129b3
DOI
10.21203/rs.3.rs-7510513/v1
Open publication

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Study on the Gene Regulatory Effects in Leukemia Based on Multi-omics Mendelian Randomization, Network Pharmacology, and Functional ValidationDOI 10.21203/rs.3.rs-7510513/v1
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