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Article

Tumor Expression Quantitative Trait Methylation Screening Reveals Distinct CpG Panels for Deconvolving Cancer Immune Signatures.

Cancer research - 3 May 2022

Yu Xiaoqing, Cen Ling, Chen Y Ann, Markowitz Joseph, Shaw Timothy I, Tsai Kenneth Y, Conejo-Garcia Jose R, Wang Xuefeng

Abstract excerpt

DNA methylation signatures in tumors could serve as reliable biomarkers that are accessible in archival tissues for tracking the epigenetic dynamics shaped by both cancer cells and the tumor microenvironment. However, given the ultrahigh dimensionality and noncollapsible nature of the data, it remains challenging to screen all CpG sites to identify the most promising marker panels. In this article, we introduce...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35176128
DOI: 10.1158/0008-5472.CAN-21-3113
PMCID: PMC9064917

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TCF7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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