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DNA methylation regulator-based modification patterns define distinct immune phenotypes and immunotherapy responses in colorectal cancer

2022-07-18

Abstract excerpt

<h4>Background: </h4> A major challenge in immunotherapy is identifying populations that can benefit from treatment. DNA methylation is one of the most extensively studied epigenetic regulation mechanisms and reportedly involved in immune regulation and anticancer immune responses. How the integrated DNA methylation modification pattern affects the tumor microenvironment (TME) and the response to immunotherapy is...

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Literature Corpus work
9de2fd07-de7e-5f69-a9b8-bf3999b3ca6a
DOI
10.21203/rs.3.rs-1819659/v1
Open publication

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