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A four-DNA methylation biomarker is a superior predictor of survival of patients with cutaneous melanoma

3 Jun 2019

Abstract excerpt

Cutaneous melanoma (CM) is a life-threatening form of skin cancer. Prognostic biomarkers can reliably stratify patients at initial melanoma diagnosis according to risk, and may inform clinical decisions. Here, we performed a retrospective, cohort-based study analyzing genome-wide DNA methylation of 461 patients with CM from the TCGA database. Cox regression analyses were conducted to establish a four-DNA...

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PMID: 31169496
DOI: 10.7554/elife.44310

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