Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotypic and phenotypic landscapes of 51 pharmacogenes derived from whole-genome sequencing in a Thai population.

PloS one - 1 Jan 2022

Wankaew Natnicha, Chariyavilaskul Pajaree, Chamnanphon Monpat, Assawapitaksakul Adjima, Chetruengchai Wanna, Pongpanich Monnat, Shotelersuk Vorasuk

Abstract excerpt

Differences in drug responses in individuals are partly due to genetic variations in pharmacogenes, which differ among populations. Here, genome sequencing of 171 unrelated Thai individuals from all regions of Thailand was used to call star alleles of 51 pharmacogenes by Stargazer, determine allele and genotype frequencies, predict phenotype and compare high-impact variant frequencies between Thai and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Healthy Volunteers

Share to High-Throughput Nucleotide Sequencing

Share to Pharmacogenetics

Share to Thailand

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 35176049
DOI: 10.1371/journal.pone.0263621
PMCID: PMC8853512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotypic and phenotypic landscapes of 51 pharmacogenes derived from whole-genome sequencing in a Thai population.PMID 35176049Read ↗

Phenotype prediction and characterization of 25 pharmacogenes in Thais from whole genome sequencing for clinical implementation.Semantic proximity Read ↗

A comprehensive Thai pharmacogenomics database (TPGxD-1): Phenotype prediction and variants identification in 942 whole-genome sequencing data.Semantic proximity Read ↗

Pharmacogenomic landscape of the Thai population from genome sequencing of 949 individuals.Semantic proximity Read ↗

Thai pharmacogenomics database -2 (TPGxD-2) sequel to TPGxD-1, analyzing genetic variants in 26 non-VIPGx genes within the Thai population.Semantic proximity Read ↗

Pharmacogenomic landscape in Thailand: Array-based profiling and EMR-linked medication exposure.Semantic proximity Read ↗

Pharmacogenetic analysis of structural variation in the 1000 genomes project using whole genome sequences.Semantic proximity Read ↗

Targeted Next-Generation Sequencing for Comprehensive Genetic Profiling of Pharmacogenes.Semantic proximity Read ↗

Frequencies of pharmacogenomic alleles across biogeographic groups in a large-scale biobank.Semantic proximity Read ↗

Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences.Semantic proximity Read ↗

PharmGKB: understanding the effects of individual genetic variants.Semantic proximity Read ↗

Analytical and Clinical Validation of Action PharmaKitDx: A Comprehensive NGS Panel for the Identification of Pharmacogenetic Variants in Diverse PopulationsSemantic proximity Read ↗

The global spectrum of protein-coding pharmacogenomic diversity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.