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Thai pharmacogenomics database -2 (TPGxD-2) sequel to TPGxD-1, analyzing genetic variants in 26 non-VIPGx genes within the Thai population.

Clinical and translational science - 1 Oct 2024

John Shobana, Klumsathian Sommon, Own-Eium Paravee, Charoenyingwattana Angkana, Eu-Ahsunthornwattana Jakris, Sura Thanyachai, Dejsuphong Donniphat, Sritara Piyamitr, Vathesatogkit Prin, Thongchompoo Nartthawee, Thabthimthong Wiphaporn, Teerakulkittipong Nuttinee, Chantratita Wasun, Sukasem Chonlaphat

Abstract excerpt

Next-generation sequencing (NGS) has transformed pharmacogenomics (PGx), enabling thorough profiling of pharmacogenes using computational methods and advancing personalized medicine. The Thai Pharmacogenomic Database-2 (TPGxD-2) analyzed 948 whole genome sequences, primarily from the Electricity Generating Authority of Thailand (EGAT) cohort. This study is an extension of the previous Thai Pharmacogenomic...

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Identifiers

PMID: 39449569
DOI: 10.1111/cts.70019
PMCID: PMC11502937

Genes

POR
CYP1B1
CYP2F1
CYP4A11
SLCO1B3
SLCO2B1
TBXAS1
UGT2B7

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