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Article

Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences.

Clinical pharmacology and therapeutics - 1 Dec 2019

Lee Seung-Been, Wheeler Marsha M, Thummel Kenneth E, Nickerson Deborah A

Abstract excerpt

Variation in the enzymatic activity of pharmacogenes is defined by star alleles (haplotypes) comprised of single-nucleotide variants, small insertion-deletions, and large structural variants. We recently developed Stargazer, a next-generation sequencing-based tool to call star alleles for the clinically important CYP2D6 gene. Here, we present the utility of extending Stargazer to call star alleles for 28...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31206625
DOI: 10.1002/cpt.1552
PMCID: PMC6896231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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