Article
Phenotype prediction and characterization of 25 pharmacogenes in Thais from whole genome sequencing for clinical implementation.
Scientific reports - 3 Nov 2020
Mauleekoonphairoj John, Chamnanphon Monpat, Khongphatthanayothin Apichai, Sutjaporn Boosamas, Wandee Pharawee, Poovorawan Yong, Nademanee Koonlawee, Pongpanich Monnat, Chariyavilaskul Pajaree
Abstract excerpt
Publicly available pharmacogenomics (PGx) databases enable translation of genotype data into clinically actionable information. As variation within pharmacogenes is population-specific, this study investigated the spectrum of 25 clinically relevant pharmacogenes in the Thai population (n = 291) from whole genome sequencing. The bioinformatics tool Stargazer was used for phenotype prediction, through assignment of...
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