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Article

Assessment of the performance of different imputation methods for low-coverage sequencing in Holstein cattle.

Journal of dairy science - 1 Apr 2022

Teng Jun, Zhao Changheng, Wang Dan, Chen Zhi, Tang Hui, Li Jianbin, Mei Cheng, Yang Zhangping, Ning Chao, Zhang Qin

Abstract excerpt

Low-coverage sequencing (LCS) followed by imputation has been proposed as a cost-effective genotyping approach for obtaining genotypes of whole-genome variants. Imputation performance is essential for the effectiveness of this approach. Several imputation methods have been proposed and successfully applied in genomic studies in human and other species. However, there are few reports on the performance of these...

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PMID: 35151474
DOI: 10.3168/jds.2021-21360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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