Article
Physiological Responses of Ribosomal Protein S12 K43 Mutants of Corynebacterium glutamicum.
Current microbiology - 10 Feb 2022
Zhao Guihong, Su Rui, Yuan Meng, Ma Hongkun, Bo Taidong, Jiang Hao, Wu Chen, Li Yanjun
Abstract excerpt
Bacterial resistance to streptomycin is often acquired as a consequence of mutations in rpsL, the gene encoding ribosomal protein S12. Corynebacterium glutamicum is a non-pathogenic Gram-positive soil bacterium that has been widely used in industry. In a previous study, we screened several streptomycin-resistant rpsL K43 mutants of C. glutamicum, and surprisingly found that two of them also confer chloramphenicol...
Topics
- Anti-Bacterial Agents
- Corynebacterium glutamicum
- Mutation
- Ribosomal Proteins
- Streptomycin