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Article

Alterations in the transcription factors GntR1 and RamA enhance the growth and central metabolism of Corynebacterium glutamicum.

Metabolic engineering - 1 Jul 2018

Wang Zhihao, Liu Jianming, Chen Lin, Zeng An-Ping, Solem Christian, Jensen Peter Ruhdal

Abstract excerpt

Evolution, i.e. the change in heritable characteristics of biological populations over successive generations, has created the diversity of life that exists today. In this study we have harnessed evolution to create faster growing mutants of Corynebacterium glutamicum, i.e. to debottleneck growth rate of this highly important industrial workhorse. After approximately 1500 generations of Adaptive Laboratory...

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PMID: 29753071
DOI: 10.1016/j.ymben.2018.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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