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Article

Genome shuffling improves thermotolerance and glutamic acid production of Corynebacteria glutamicum.

World journal of microbiology & biotechnology - 1 Mar 2012

Zheng Pu, Liu Miao, Liu Xiao-de, Du Qiao-Yan, Ni Ye, Sun Zhi-Hao

Abstract excerpt

Genome shuffling was used to improve the thermotolerance of L: -glutamic acid-producing strain Corynebacteria glutamicum. Five strains with subtle improvements in high temperature tolerance and productivity were selected by ultraviolet irradiation and diethyl sulfate mutagenesis. An improved strain (F343) was obtained by three rounds of genome shuffling of the five strains as mentioned above. The cell density of...

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PMID: 22805825
DOI: 10.1007/s11274-011-0902-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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