Article
Genetic landscape of human platelet antigen variants in the Indian population analysed from 1029 whole genomes.
International journal of immunogenetics - 1 Jun 2023
Rophina Mercy, Bhoyar Rahul C, Imran Mohamed, Senthivel Vigneshwar, Divakar Mohit Kumar, Mishra Anushree, Vatsyayan Aastha, Jolly Bani, Sivasubbu Sridhar, Scaria Vinod
Abstract excerpt
Genetic variants in human platelet antigens (HPAs) considered allo- or auto antigens are associated with various disorders, including neonatal alloimmune thrombocytopenia, platelet transfusion refractoriness and post-transfusion purpura. Although global differences in genotype frequencies were observed, the distributions of HPA variants in the Indian population are largely unknown. This study aims to explore the...
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