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Article

Toll-Like Receptors (TLRs) in Health and Disease: An Overview.

Handbook of experimental pharmacology - 1 Jan 2022

Kumar Vijay, Barrett James E

Abstract excerpt

Toll-like receptors were discovered as proteins playing a crucial role in the dorsoventral patterning during embryonic development in the Drosophila melanogaster (D. melanogaster) almost 40 years ago. Subsequently, further research also showed a role of the Toll protein or Toll receptor in the recognition of Gram-positive bacterial and fungal pathogens infecting D. melanogaster. In 1997, the human homolog was...

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PMID: 35091824
DOI: 10.1007/164_2021_568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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