Article
Immune interventions of human diseases through toll-like receptors.
Advances in experimental medicine and biology - 1 Jan 2009
Coban Cevayir, Ishii Ken J, Akira Shizuo
Abstract excerpt
Toll-like receptors (TLRs) are the immune sensors for infections, triggering robust innate immune activation followed by protective adaptive immunity against various infectious diseases. Recent evidence, however, has suggested that TLRs are involved in the pathogenesis of many diseases, including not only infectious diseases but also autoimmune diseases, allergy and atherosclerosis. Therefore, prophylactic or...
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