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Toll-like receptor 4: A potential therapeutic target for multiple human diseases

16 Aug 2023

Abstract excerpt

The immune response plays a pivotal role in the pathogenesis of diseases. Toll-like receptor 4 (TLR4), as an intrinsic immune receptor, exhibits widespread in vivo expression and its dysregulation significantly contributes to the onset of various diseases, encompassing cardiovascular disorders, neoplastic conditions, and inflammatory ailments. This comprehensive review centers on elucidating the architectural and...

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PMID: 37595428
DOI: 10.1016/j.biopha.2023.115338

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