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Article

Whole-Genome Sequencing for Resistance Level Prediction in Multidrug-Resistant Tuberculosis.

Microbiology spectrum - 29 Jun 2022

Li Jinli, Yang Tingting, Hong Chuangyue, Yang Zheng, Wu Likai, Gao Qian, Yang Hui, Tan Weiguo

Abstract excerpt

Defining the precise relationship between resistance mutations and quantitative phenotypic drug susceptibility testing will increase the value of whole-genome sequencing (WGS) for predicting tuberculosis drug resistance. However, a large number of WGS data sets currently lack corresponding quantitative phenotypic data-the MICs. Using MYCOTBI plates, we determined the MICs to nine antituberculosis drugs for 154...

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Identifiers

PMID: 35658579
DOI: 10.1128/spectrum.02714-21
PMCID: PMC9241708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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