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Article

Mitochondrial-nuclear epistasis underlying phenotypic variation in breast cancer pathology.

Scientific reports - 26 Jan 2022

Bushel Pierre R, Ward James, Burkholder Adam, Li Jianying, Anchang Benedict

Abstract excerpt

The interplay between genes harboring single nucleotide polymorphisms (SNPs) is vital to better understand underlying contributions to the etiology of breast cancer. Much attention has been paid to epistasis between nuclear genes or mutations in the mitochondrial genome. However, there is limited understanding about the epistatic effects of genetic variants in the nuclear and mitochondrial genomes jointly on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35082309
DOI: 10.1038/s41598-022-05148-4
PMCID: PMC8791930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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