Article

A Sexual Bias in mitochondrial protein-coding gene expression across different tissues and the prognostic value in multiple cancers

2022-11-24

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondria in mammalian cells provide ATP through oxidative phosphorylation. The overproduction of reactive oxygen species (ROS) in mitochondrial cells promotes cancer by modifying gene expression or function. Mating introduces competing mitochondrial (mtDNA) and nuclear DNA (nDNA) gene products, leading to biological differences between males and females for diseases and disorders such as can...

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Literature Corpus work: 0f6693dd-fcb8-5e18-90e0-426a216f39d9
DOI: 10.1101/2022.11.22.517535

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