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Article

Association between Maternal Drug Use and Cytochrome P450 Genetic Polymorphisms and the Risk of Congenital Heart Defects in Offspring.

Biomedical and environmental sciences : BES - 20 Jan 2022

Qin Jia Bi, Luo Liu, Sun Meng Ting, Huang Peng, Wang Ting Ting, Zhang Sen Mao, Li Jin Qi, Li Yi Huan, Chen Le Tao, Diao Jing Yi, Zhu Ping

Abstract excerpt

OBJECTIVE: This study aimed to assess the associations between maternal drug use, cytochrome P450 ( CYP450) genetic polymorphisms, and their interactions with the risk of congenital heart defects (CHDs) in offspring. METHODS: A case-control study involving 569 mothers of CHD cases and 652 controls was conducted from November 2017 to January 2020. RESULTS: After adjusting for potential confounding factors, the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 35078561
DOI: 10.3967/bes2022.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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